{"id":308,"date":"2020-07-18T22:08:56","date_gmt":"2020-07-18T19:08:56","guid":{"rendered":"https:\/\/f-genetics.com\/?page_id=308"},"modified":"2026-03-31T17:07:18","modified_gmt":"2026-03-31T14:07:18","slug":"exom","status":"publish","type":"test","link":"https:\/\/f-genetics.com\/en\/exom\/","title":{"rendered":"Exome sequencing"},"content":{"rendered":"

What is exome sequencing?<\/h2>
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Exome<\/div>
Indications<\/div>
Features<\/div>
How it works<\/div>
Advantages<\/div>
Glossary<\/div><\/div><\/div>
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Genetic information is an instruction for each cell in our body, which contains the mechanism for development and functioning. This information is stored in the form of DNA molecules, which are made up of four chemical compounds (bases) designated by the letters A, T, C and G (adenine, thymine, cytosine and guanine).<\/p>\n\n\n\n

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Changes in this sequence can distort important information, disrupting habitual cellular mechanisms and causing disease<\/p>\n<\/div>\n<\/div>\n\n\n\n

Consistently connected to one another, these bases serve as carriers of information that is received from parents and will be passed on to children, in a form that our cells can recognise.<\/p>\n\n\n\n

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The human body is made up of cells and cells contain DNA. Genes provide information for the synthesis of all proteins in the body<\/p>\n<\/div>\n<\/div>\n\n\n\n

All of a person's genetic information is their genome, and its complete record in the form of a DNA molecule is represented by a sequence of over 3.2 billion bases. But only 1% (30 million nucleotide pairs) of this sequence is in the exome.<\/p>\n\n\n\n


Exome<\/strong> is the part of the genome responsible for protein synthesis in the body.<\/p>\n\n\n\n

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For clinical purposes, data from exome reading is sufficient in most cases.<\/p>\n<\/div>\n\n\n\n

85%<\/span>of all disease-related mutations are mutations in the exome<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Indications for the test<\/h3>\n\n\n\n
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