{"id":4286,"date":"2021-12-08T09:58:00","date_gmt":"2021-12-08T06:58:00","guid":{"rendered":"https:\/\/f-genetics.com\/?post_type=test&p=4286"},"modified":"2025-10-19T20:24:01","modified_gmt":"2025-10-19T17:24:01","slug":"carrier-seq","status":"publish","type":"test","link":"https:\/\/f-genetics.com\/en\/carrier-seq\/","title":{"rendered":"Carrier Seq"},"content":{"rendered":"

What are the risks of a couple passing on a genetic disease to their child?<\/h2>
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Carrier<\/div>
Types and Prevalence\u00a0<\/div>
Prevention<\/div><\/div><\/div>
\u2190<\/div>
\u2192<\/div>
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Approximately 1 out of every 200<\/strong>[1] <\/sup>couples in the general population is at risk of being carriers of an inherited genetic disease[2]<\/sup>.<\/p>\n\n\n\n

Carrier<\/strong> is a person who has a genetic variation in their DNA associated with the disease and might pass it on to the next generation.<\/p>\n\n\n\n

An inherited genetic disease<\/strong> is a pathological condition of the body caused by an abnormality in a certain gene. The result of the abnormality in the DNA can range from asymptomatic to serious life-threatening health issues.<\/p>\n\n\n\n

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1 \u0438\u0437 200<\/span>The incidence of hereditary diseases in newborns is 1 in 200 [4]<\/sup>.<\/span><\/p>\n\n\n

6000<\/span>hereditary diseases have been identified to date [3]<\/sup>.<\/span><\/p>\n<\/div>\n\n\n\n

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With a seemingly low incidence of genetic diseases, an average incidence of carriage of altered genes in healthy population is 1 per 20-50 people<\/strong>.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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All inherited diseases are caused by changes in a specific gene and are known as monogenic or Mendelian disorders.<\/p>\n<\/div>\n\n\n\n

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Types and Prevalence:<\/strong> <\/h3>\n\n\n\n